X-Nico

unusual facts about class I MHC



Interferon gamma

Cause normal cells to increase expression of class I MHC molecules as well as class II MHC on antigen presenting cells—specifically through induction of antigen processing genes, including subunits of the immunoproteasome (MECL1, LMP2, LMP7), as well as TAP and ERAAP in addition possibly to the direct upregulation of MHC heavy chains and B2-microglobulin itself


see also