α-Lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and β-1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component.
One form of C3-convertase, also known as C4b2a, is formed by a heterodimer of activated forms of C4 and C2.
This interlocking domain forms a 3-helical non-globular array that forms interlocked heterodimers with its target.
The granulocyte macrophage colony-stimulating factor receptor is a heterodimer composed of at least two different subunits; an α chain, and a β chain which is also present in the receptors for IL-3 and IL-5.
Glutamate-cysteine ligase, catalytic (Gclc) and glutamate-cysteine ligase, modifier (GCLM) subunits form a heterodimer, which is the rate-limiting step in the synthesis of glutathione (GSH), a very powerful endogenous antioxidant.
Clock- The clock gene in Drosophila encodes for the CLOCK protein and forms a heterodimer with the protein CYCLE in order to control the main oscillating activity of the circadian clock.
Heterodimer CLOCK-BMAL1 activates E-box elements present in the Per1 promoter, as well activating the E box promoters of other components of the molecular clock such as PER2, CRY1, and CRY2.
SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins.