Macrophage-1 antigen (or integrin αMβ2) is a complement receptor ("CR3") consisting of CD11b (integrin αM) and CD18 (integrin β2).
MΦ (not to be confused with MØ), an abbreviation for Macrophages, cells produced by the differentiation of monocytes in tissues.
Macrophage migration inhibitory factor | macrophage | Macrophage | Granulocyte macrophage colony-stimulating factor receptor |
In a study conducted by Jürg Gertsch et al. from the Swiss Federal Institute of Technology (ETH Zurich), beta-caryophyllene was shown to be selective agonist of cannabinoid receptor type-2 (antiinflammatory effects in mice.
The molecule is bound to a tumour cell via the tumour antigen CD30 and to a macrophage via an Fc receptor.
Collagens XIII, XVII, and XXV, and related proteins such as class A macrophage scavenger receptors, ectodysplasin A or the MARCO1 receptor, are also part of this group.
In EG cytokines IL-3, IL-5 and granulocyte macrophage colony stimulating factor (GM-CSF) may be behind the recruitement and activation.
The granulocyte macrophage colony-stimulating factor receptor is a heterodimer composed of at least two different subunits; an α chain, and a β chain which is also present in the receptors for IL-3 and IL-5.
In 1898, after several years of research, Tadeusz Browicz, a Polish scientist, identified them, correctly, as macrophages.
Macrophage colony-stimulating factor has been shown to interact with PIK3R2.