X-Nico

unusual facts about nucleic acid



Dihydrofolic acid

Since tetrahydrofolate is needed to make both purines and pyrimidines, which are building blocks of DNA and RNA, dihydrofolate reductase is targeted by various drugs to prevent nucleic acid synthesis.

International Committee on Taxonomy of Viruses

The database classifies viruses based primarily on their chemical characteristics, genomic type, nucleic acid replication, diseases, vectors, and geographical distribution, among other characteristics.

Spectrophotometer for Nucleic Acid Measurements

Analysis of nucleic acids is commonly performed to determine the average concentrations of DNA or RNA present in a mixture, as well as their purity.

Ultraviolet germicidal irradiation

It is effective in destroying the nucleic acids in these organisms so that their DNA is disrupted by the UV radiation, leaving them unable to perform vital cellular functions.


see also

Aptamer

While the process of artificial engineering of nucleic acid ligands is highly interesting to biology and biotechnology, the notion of aptamers in the natural world had yet to be uncovered until 2002 when two groups led by Ronald Breaker and Evgeny Nudler discovered a nucleic acid-based genetic regulatory element (which was named riboswitch) that possesses similar molecular recognition properties to the artificially made aptamers.

HindIII

They have proven to be ideal modeling systems for the study of protein-nucleic acid interactions, structure-function relationships, and the mechanism of evolution.

Margaret Oakley Dayhoff

It and the parallel effort by Walter Goad which led to the GenBank database of nucleic acid sequences are the twin origins of the modern databases of molecular sequences.

Quadruplex

G-quadruplex, the four-stranded nucleic acid structure that is, among scientists, sometimes referred to as a quadruplex.

Sarepta Therapeutics

Its primary products are Morpholino oligomers (PMOs), synthetic nucleic acid analogs that were conceived of by James Summerton and invented by Summerton with Dwight Weller, and are being developed under the name NeuGene Antisense.

Therapeutic target

Biological target, a protein or nucleic acid whose activity can be modified by an external stimulus

Threose nucleic acid

Threose nucleic acid (TNA) is an artificial genetic polymer invented by Albert Eschenmoser.

Wilma Olson

Wilma Olson was involved in setting up the nucleic acid database, in collaboration with Helen M. Berman.