X-Nico

unusual facts about nucleotides



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50S

The model of Hm 50S determined in 2000 by Nenad Ban and colleagues in the laboratory of Thomas Steitz includes 2711 of the 2923 nucleotides of 23S rRNA, all 122 nucleotides of its 5S rRNA, and structure of 27 of its 31 proteins.

Adenylosuccinate lyase deficiency

ASL catalyzes two distinct reactions in the synthesis of purine nucleotides, both of which involve the β-elimination of fumarate to produce either aminoimidazole carboxamide ribotide (AICAR) from SAICAR or adenosine monophosphate (AMP) from S-AMP.

Cis-natural antisense transcript

RNA polymerases will then begin transcribing the gene at the transcription initiation site laying down nucleotides in a 5' to 3' direction.

Data compression

Genetics compression algorithms are the latest generation of lossless algorithms that compress data (typically sequences of nucleotides) using both conventional compression algorithms and genetic algorithms adapted to the specific datatype.

Junctional diversity

Exonucleases remove these unpaired nucleotides and the gaps are filled by DNA synthesis and repair machinery.

M13 bacteriophage

M13 is a filamentous bacteriophage composed of circular single stranded DNA (ssDNA) which is 6407 nucleotides long encapsulated in approximately 2700 copies of the major coat protein P8, and capped with 5 copies of two different minor coat proteins (P9, P6, P3) on the ends.

Molecular beacon

The middle 15 nucleotides are complementary to the target DNA or RNA and do not base pair with one another, while the five nucleotides at each terminus are complementary to each other rather than to the target DNA.

Motif

Sequence motif, a sequence pattern of nucleotides in a DNA sequence or amino acids in a protein

Single-molecule magnetic sequencing

After the RNase cleavage of the last six nucleotides, the next step is phosphorylation of the 5'-end via Kinase.

Stephen Altschul

Most notably, Altschul is the co-author of the BLAST algorithm used for sequence analysis of proteins and nucleotides.

Transposon silencing

Piwi-interacting RNA (piRNA), the largest class of the small RNAs, are between 26 and 31 nucleotides in length and function through interactions with piwi proteins from the Argonaute protein family (gene silencing proteins).


see also