X-Nico

41 unusual facts about Alzheimer’s disease


Aquarium therapy

A Purdue study in 2009 examined the effect of aquariums on the nutritional intake of patients diagnosed with Alzheimer's disease.

Arthur O'Connell

At the time of his death from Alzheimer's disease in California in May 1981, O'Connell was appearing by his own choice solely in these commercials.

ASAH2B

ASAH2B shows reduced expression with increasing age and further reduction in late onset Alzheimer's disease patients.

Bill Lawton

Lawton died in Brighton on 14 August 2008 following a battle with Alzheimer's disease.

Braak staging

The Braak staging is a method used to classify the degree of pathology in Parkinson's disease and Alzheimer's disease.

Center for BrainHealth

All contributions support the cause of brain health and the Center’s many research focus areas-Alzheimer's disease, traumatic brain injury (TBI), autism, Attention Deficit Hyperactivity Disorder (ADHD), stroke, Post-Traumatic Stress Disorder (PTSD), Addiction, BrainHealth Physical, Dementia, Exercise and the Brain, Healthy Brain Aging, and Virtual Brain Training.

The Center provides academic training and houses specialists in, among many others, Alzheimer's disease, traumatic brain injury (TBI), healthy brain aging, autism, Attention Deficit Hyperactivity Disorder (ADHD), stroke, and Post-Traumatic Stress Disorder (PTSD).

Cerlapirdine

Cerlapirdine (USAN; SAM-531, WAY-262,531, PF-05212365) is a drug which is under development by Wyeth/Pfizer for the treatment of cognitive disorders associated with Alzheimer's disease and schizophrenia.

Christian Haass

The emphasis of his work is in the molecular biology and cell biology of Alzheimer's disease and Parkinson's disease.

Daniel Bekker

Bekker died on 22 October 2009 after a long struggle with Parkinson's and Alzheimer's diseases.

Duilio Loi

His daughter accepted the award on his behalf, because Loi was suffering from Alzheimer's.

Elegy for Iris

Elegy for Iris is a 1999 memoir by John Bayley, about his marriage to fellow author Iris Murdoch, who suffered from Alzheimer's disease in her last years.

Elizabeth Fabac

Elizabeth Fabac Bretting died in 2008, aged 86, following complications from Alzheimer's disease.

Expressive therapy

The documentary I Remember Better When I Paint is an international film which documents the positive impact of art and other creative activities on people with Alzheimer's disease.

Fernand Mousseau

Mousseau died in Gatineau, on April 26, 2010 from Alzheimer's.

Gnarly Buttons

He has also stated that Gnarly Buttons was influenced in part by his father’s passing due to Alzheimer's disease.

Hippocampal prosthesis

Because of its close relationship with memory formation, damage to the hippocampus is closely related to Alzheimer disease.

Homotaurine

Homotaurine has also been investigated as a potential treatment for Alzheimer's disease.

Human Connectome Project

The goal of the Human Connectome Project is to build a "network map" that will shed light on the anatomical and functional connectivity within the healthy human brain, as well as to produce a body of data that will facilitate research into brain disorders such as dyslexia, autism, Alzheimer's disease, and schizophrenia.

Ispronicline

It has antidepressant, nootropic and neuroprotective effects, and is under development for the treatment of dementia and Alzheimer's disease.

Jakeem Thunder

Also in the course of the battle with Grundy, Jakeem unwittingly cures his predecessor, Johnny Thunder, of his Alzheimer's disease.

Kynapcin

Like polyozellin, it inhibits prolyl endopeptidase, an enzyme that has a role in processing proteins (specifically, amyloid precursor protein) in Alzheimer's disease.

Martin Tytell

He died in the Bronx of cancer on September 11, 2008 while also suffering from Alzheimer's disease.

Meclofenoxate

Meclofenoxate (Lucidril), also known as centrophenoxine, is a drug used to treat the symptoms of senile dementia and Alzheimer's disease.

Music therapy for Alzheimer's disease

Music therapy (MT) is one of the most common treatments for Alzheimer's disease (AD).

Nusrat Bhutto

For the last several years of her life, she had also been suffering from Alzheimer's disease.

She lived the last few years of her life with her daughter's family in Dubai, United Arab Emirates and later suffered from the combined effects of a stroke and Alzheimer's disease.

Peggy Ramsay

Ramsay, whose last years were affected by the onset of Alzheimer's disease, died on 4 September 1991 in London.

Polyozellin

It inhibits prolyl endopeptidase, an enzyme that has a role in processing proteins (specifically, amyloid precursor protein) in Alzheimer's disease.

PPP3R1

The presence of a single nucleotide polymorphism rs1868402 in the PPP3R1 gene is strongly correlated with rapid progress of Alzheimer's disease.

Raj Singh Dungarpur

He died on 12 September 2009 after a prolonged battle with Alzheimer's disease, in Mumbai.

Raymond Bailey

He reportedly began suffering symptoms of Alzheimer's disease, which visibly affected his performance in the last episodes of The Beverly Hillbillies, and he was completely unable to work after 1975.

Rivastigmine

Rivastigmine (sold under the trade name Exelon) is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and dementia due to Parkinson's disease.

Robert L. Miller

In his last four years, Miller was afflicted with Alzheimer's disease.

Roger Donoghue

Donoghue died in Greenport, New York of complications from Alzheimer's disease.

Sacrifices of the Heart

By the time he is formally diagnosed with serious Alzheimer's disease, Kate realizes how much she doesn't know her family, having run from her past after the trauma of witnessing her mother's suicide at age seven.

Synaptic fatigue

Hallmarks of Alzheimer's disease (AD) are impairment of cognition, aggregation of β-amyloid peptide (Aβ), neurofibrillary degeneration, loss of neurons with accelerated atrophy of specific brain areas, and decrease of synapse number in surviving neurons.

Thorpe Coombe Hospital

It ceased maternity facilities in 1973 and was subsequently used as a nurses' home, then a treatment centre for Alzheimer's disease patients, and latterly an out-patients and inpatient service psychiatric hospital.

Virginia Pep Band

The ensemble has also performed at Charlottesville community events including the Charlottesville 10-miler, the Alzheimer's Walk, and the United Way Day of Caring.

William C. Winfrey

A resident of San Clemente, California, he died at age seventy-seven of complications from Alzheimer's disease.

ZM-241,385

In animal models, ZM-241,385 has been shown to protect against beta amyloid neurotoxicity and therefore may be useful as a treatment for Alzheimer's disease.


Alzheimer's Association, Central New York Chapter

Regional offices are located in the Nichols Notch Building at 401 Hayes Avenue in Endicott; 258 Genesee Street in Utica; and the HSBC Bank Building at 120 Washington Street, Suite 419, in Watertown.

Alzheimer's Research UK

In March 2008, author Terry Pratchett, who has the disease, donated one million US dollars to the trust.

Angus Reid

Reid missed three years of college football at Simon Fraser because of gastrointestinal problems linked to Crohn's disease but he played every CFL game from the 2002 to 2008 CFL seasons including the 92nd and 94th Grey Cups.

Antanas Mockus

On 9 April 2010 he announced that he had been diagnosed with Parkinson's disease.

APOE

Apolipoprotein E, a main apoprotein of the chylomicron, also studied for its involvement in Alzheimer's Disease risk.

Bugula

In January 2008 a clinical trial was submitted to the United States National Institutes of Health to measure the safety and effectiveness of Bryostatin 1 in the treatment of Alzheimer's Disease.

Carol Carr

Carol Scott Carr (born 1939) is an American woman from the state of Georgia who became the center of a widely publicized debate over euthanasia when she killed her adult sons because they were suffering from Huntington's disease.

Cell therapy

Neural stem cells (NSCs) are the subject of ongoing research for possible therapeutic applications, for example for treating a number of neurological disorders such as Parkinson's disease and Huntington's disease.

Charles Enrique Dent

He began research into a hereditary disease of the kidneys which was greatly expanded by his pupil Oliver Wrong and named Dent's disease.

Charles Stoneham

For several years before his death, Stoneham had been suffering from a variety of physical ailments which were eventually diagnosed as symptoms of Bright's disease.

Charles W. Morse

In 1912 Morse became ill, and a panel of Army doctors declared that he suffered from Bright's disease and other maladies and would soon die if he remained in prison.

Conghua city yueyuan animal breeding farm

The monkeys are used scientific research, including gene therapy, cancer, Parkinson's, Alzheimer's, stem cells and antibody-based treatments.

Denise Holt

She is a Board member of Ofqual (the examinations regulator in England), a member of the NHS Pay Review Body, and Independent Chair of the nominations committee of the Alzheimer's Society.

First Cousin Once Removed

Documentary about the life of poet, translator, critic and university professor Edwin Honig and his struggles with Alzheimer's disease.

Hereditary Disease Foundation

In 1968, after experiencing Huntington's disease (HD) in his wife's family, Dr. Milton Wexler was inspired to start the Hereditary Disease Foundation, with the aim of curing genetic illnesses by coordinating and supporting research.

Hes3 signaling axis

:* Activation of the signaling pathway by Delta4, Angiopoietin 2, insulin, or a combination of the three and a JAK inhibitor induces motor skill improvements in adult rat models of Parkinson's disease (6-hydroxydopamine model).

Hoxton Square

James Parkinson (1755–1824), the physician and author of An Essay on the Shaking Palsy, the subject of which is now known as Parkinson's disease, was in practice at 1 Hoxton Square, which is commemorated with a blue plaque on the site.

Hyperkinesia

Hyperkinesia is a state of excessive restlessness which is featured in a large variety of disorders that affect the ability to control motor movement, such as Huntington's disease.

Jean Kasem

In October 2013, Kerri Kasem, one of Casey Kasem's three children from his first marriage, said her father was suffering from Parkinson's disease.

Jean-Louis Tauran

In spite of having Parkinson's disease, Tauran was appointed as president of the Pontifical Council for Interreligious Dialogue on 25 June 2007, showing that the disease was not getting worse and he was able to handle more responsibility.

Larry Whiteside

Whiteside developed Parkinson's disease early in the 21st century, which led to the end of his career with The Boston Globe in 2004.

Low-threshold spikes

Therefore, much research has been conducted on low-threshold spikes in the neurons in the thalamus and how it could relate to Parkinson's disease and the corresponding loss of motor function.

Mieczysław Weinberg

Towards the end of his life, Weinberg suffered from Crohn's disease and remained housebound for the last three years, although he continued to compose.

Muscimol

In patients with Huntington's disease and chronic schizophrenia, oral doses of muscimol have been found to cause a rise of both prolactin and growth hormone.

My Angel My Hero

The film tells the story of a young boy Billy (Dakim Wills), who is suffering from Parkinson's disease and dances in New York City subway and streets.

Mycobacterium avium subspecies paratuberculosis

On the assumption that MAP is a causative agent in Crohn's disease, the Australian biotechnology company Giaconda is seeking to commercialize a combination of rifabutin, clarithromycin, and clofazimine as a potential drug therapy, called Myoconda, for Crohn's.

New investigator

Other organizations, such as the Alzheimer's Association, consider a new investigator someone that is less than 10 years past their PhD degree.

Parkinson Association of the Rockies

The Parkinson Association of the Rockies (PAR) is a Colorado care and research not-for-profit organization whose aim is to enhance the quality of life for individuals with Parkinson's disease through education, research, awareness and support for those with Parkinson's disease, their families and the community.

Parsons, Kansas

The Southeast Kansas Agricultural Research Center of Kansas State University is also located on the grounds, as is the Alzheimer's Association, Heart of America Chapter, Southeast Kansas Regional Office.

Philippe Gaucher

Gaucher is remembered for his description of the disorder that was to become known as Gaucher's disease.

Presenilin

They were first identified in screens for mutations causing early onset forms of familial Alzheimer's Disease by Peter St George-Hyslop at the Centre for Research in Neurodegenerative Diseases at the University of Toronto, and now also at the University of Cambridge.

Protein losing enteropathy

Causes of protein losing enteropathy include celiac disease, Crohn's disease, short bowel syndrome (where the absorptive area for proteins is decreased), intestinal lymphangiectasia, amyloidosis, enteropathy caused by NSAIDs, Ménétrier's disease, dyskeratosis congenita, IPEX and giardiasis.

Rogelio Frigerio

Frigerio lost his friend, Arturo Frondizi, to Parkinson's disease in 1995, and his own health declined subsequently.

Solid-state nuclear magnetic resonance

Membrane proteins and amyloid fibrils, the latter related to Alzheimer's disease and Parkinson's disease, are two examples of application where solid-state NMR spectroscopy complements solution-state NMR spectroscopy and beam diffraction methods (e.g. X-ray crystallography, electron microscopy).

Stacy Smith

Smith has been honored as a co-anchor with awards from the Associated Press and United Press International, and for reports on Thomas Starzl and on Alzheimer's disease.

Tara Devi

After this tragedy, she became physically unfit and later was diagnosed with Parkinson's disease.

The Swedish Parkinson Academy

The main aim of the academy is to stimulate preclinical and clinical research related to Parkinson's disease, especially to support translational projects (projects bridging the border between preclinical and clinical research, bringing promising preclinical results to clinical studies).

Thioflavin

The dye is widely used to visualize and quantify the presence of misfolded protein aggregates called amyloid, both in vitro and in vivo (e.g., plaques composed of amyloid beta found in the brains of Alzheimer's disease patients).

Victoria Glendinning

Her second husband Terence de Vere White died of Parkinson's disease in 1994 and in 1996 she married Kevin O'Sullivan.

Walter Dawson

Walt Dawson (born 1982), American Alzheimer's disease activist