X-Nico

2 unusual facts about Bruton's tyrosine kinase


Ogden Bruton

The gene associated with this defect is also named after him: Btk, abbreviation for Bruton's tyrosine kinase.

X-linked agammaglobulinemia

XLA is caused by a mutation on the X chromosome of a single gene identified in 1993 which produces an enzyme known as Bruton's tyrosine kinase, or Btk.


Arthur Bartholomew

Arthur Bartholomew (3 December 1833 Bruton, Somerset – 19 August 1909 Melbourne) was an English-born Australian engraver, lithographer and natural history illustrator.

Berkeley baronets

The Berkeley Baronetcy, of Bruton in the County of Somerset, was created in the Baronetage of England on 2 July 1660 for Maurice Berkeley, eldest son of Sir Charles Berkeley, of Bruton in Somerset (who was descended from Maurice de Berkeley, 2nd Baron Berkeley).

Bruton Parish Church

The name of the parish comes from the town of Bruton, in the English county of Somerset, which was the ancestral home to several leading colonial figures, notably Virginia's colonial secretary Thomas Ludwell and the Ludwell family, as well as that of the Royal Governor, Sir William Berkeley.

C. J. Bruton

Bruton signed for the cashed-up Brisbane Bullets for the 2006/07 NBL season, joining a star-studded team that also featured Mark Bradtke, Sam Mackinnon, Dusty Rychart, Stephen Black and Adam Gibson.

Francesco Ruspoli, 3rd Prince of Cerveteri

Enrico dei Principi Ruspoli (Rome, July 25, 1878 – Nemi, December 4, 1909), married in Washington, DC, March 2, 1901 Eugenia Enfield Berry (Rome, Floyd County, Georgia, ca 1870 – 1951), formerly Mrs. Henry Bruton, without issue

Hubert Phillips

Phillips was educated at Sexey's School, Bruton, and Merton College, Oxford, where he read history and economics, taking a first class degree.

Hugh Sexey

After his death the trustees of his will established Sexey's Hospital in Bruton as an institution to care for the elderly.This included the site of Sexey's School, which still exists today.

Lauren Bruton

Bruton scored on her debut cap for the England Under-17s side, against Greece.

Music from Songwriter

# "How Do You Feel About Foolin' Around" (Kristofferson, Stephen Bruton, Mike Utley) – 2:43

Tynte baronets

He died soon after this for, in a by-election of 2 June 1661, his seat was filled by Sir John Perceval, Bart, of Bruton.


see also