In the past, Chinese hamsters were commonly used laboratory animals, until they were replaced by the common mouse and rat, which are easier to keep and breed; however, quite a few biotech drugs are still being produced by putting the gene for the protein into Chinese hamster ovary cells, which then produce the protein.
Chinese hamster ovary (CHO) cells are a cell line derived from the ovary of the Chinese hamster, often used in biological and medical research and commercially in the production of therapeutic proteins.
The main focus of his experimental work was the epigenetic control of gene expression by DNA methylation in CHO cells.
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