It was founded by Lorenz Kuenzl, a native of Bohemia in the Austrian Empire, and operated by Kuenzl, his wife Barbara Walters, and his brother-in-law.
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The brewery's main product was Chief Oshkosh Beer, named after the Menominee Chief Oshkosh (1795-1858).
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The Oshkosh Brewing Co. started in 1866 on the shores of Lake Winnebago as the Horn & Schwalm brewery.
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