Famous descendants of Isaiah Horowitz included Yaakov Yitzchak of Lublin, (Yaakov Yitzchak Horowitz; Hebrew: יעקב יצחק הורוביץ), known as "The Chozeh of Lublin" (Hebrew: החוזה מלובלין, The Seer of Lublin), the prominent Billiczer Rabbinical family of Szerencs, Hungary and the Dym family of Rabbis and communal leaders in Galicia.
Isaiah | Book of Isaiah | Vladimir Horowitz | Isaiah Washington | Isaiah Berlin | David Horowitz | Anthony Horowitz | Marc Horowitz | Jonathan Horowitz | Isaiah 7:14 | Zachary Isaiah Williams | Isaiah Thomas | David Horowitz Freedom Center | Adam Horowitz (screenwriter) | Adam Horowitz | Joseph Horowitz | Isaiah Rogers | Isaiah Mustafa | Isaiah L. Kenen | Isaiah Kacyvenski | Isaiah Horowitz | Donald L. Horowitz | David Horowitz (conservative writer) | Wayne Horowitz | The front of the Painted Bride Art Center, showing ''Skin of the Bride,'' a mosaic by Philadelphia artist Isaiah Zagar | Smackin' Isaiah | Paul Horowitz | Naftali Yehuda Horowitz | Moses Halevy Horowitz's | Michael Horowitz |
Melamed edited a new edition of the book Shnei Luchot HaBrit (the Shelah), and also edited the first two volumes in the new edition of the series of books by Rabbi Tzadok HaKohen from Lublin.
Yaakov Yitzchak was a descendant of Isaiah Horowitz (Hebrew: ישעיה הלוי הורוביץ), also known as the Shelah ha-Kadosh (Hebrew: של"ה הקדוש), a prominent Levite rabbi and mystic.