In 1560 Francis Laparelli was called to Rome by Pope Pius IV, at the request of cousin his Serbelloni, with the task of restoring the fortifications of Civitavecchia.
Toma Crijević or Tommaso Cerva (16th century) - Dominican, lawyer and outstanding jurist, was bishop of Trebinje and Mercana, director of the church of Ston between 1541 and 1559 and general vicar of the archbishop of Dubrovnik, Giovanni Angelo Medici, who became Pope Pius IV in 1559.
Paul having died just before his arrival, Castelnau used his influence in favor of the election of Pius IV.
Another legend says that at the Council of Trent a Hungarian bishop gave a taste of Tállya wine to Pope Pius IV, who said Summum pontificem talia vina decent – a Latin word play meaning "Tállya wine / This kind of wine is worthy to be on His Holiness' table!"
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Antonio del Duca or Lo Duca (Cefalù 1491 — Rome 1564) was the Sicilian friar whose persistent campaign for an official veneration of the "Seven Angelic Princes" was partly answered in the dedication of Santa Maria degli Angeli e dei Martiri, constructed to the orders of Pope Pius IV within the ruins of the Baths of Diocletian.
The construction of the Archiginnasio was commissioned by Pope Pius IV through the papal legates Charles Borromeo and Pier Donato Cesi during the years of the Council of Trent, who then entrusted the project to Antonio Morandi (known as il Terribilia), who finished the construction between 1562 and 1563.
Francesco (1680 + 1732) married Elena Attendolo Bolognini, member of an important noble family from Milan and descendant (by mother, Cecilia Medici di Marignano) from Pope Pius IV and Gian Giacomo Medici.