Formaldehyde fixes tissue or cells by irreversibly connecting a primary amine group in a protein molecule with a nearby nitrogen in a protein or DNA molecule through a -CH2- linkage called a Schiff base.
The overall pathway of glucosepane formation starts with lysine attacking the reducing sugar D-glucose to form the unstable imine known as a Schiff base, which then rearranges to form the more stable aminoketose Amadori product.
Edwards Air Force Base | Wright-Patterson Air Force Base | Guantanamo Bay Naval Base | Offutt Air Force Base | Maxwell Air Force Base | Ace of Base | Nellis Air Force Base | András Schiff | Vandenberg Air Force Base | Ramstein Air Base | Eglin Air Force Base | Marine Corps Base Quantico | Tan Son Nhut Air Base | Marine Corps Base Camp Lejeune | BASE jumping | Marine Corps Base Hawaii | Clark Air Base | base on balls | Peterson Air Force Base | MacDill Air Force Base | Lackland Air Force Base | Kadena Air Base | Joint Base Lewis-McChord | Hamilton Air Force Base | stolen base | military base | Little Rock Air Force Base | Hanscom Air Force Base | Bien Hoa Air Base | Whiteman Air Force Base |
His research group has synthesized a number of Schiff base polymers and have developed new stationary phase for Gas Chromatography and sensitive Liquid Chromatography procedures for the determination of pesticide malathion.