Bending to the north through Yonkers, the Sprain Brook enters and interchange with Tuckahoe Road, with the northbound and southbound lanes splitting around the Grassy Sprain Reservoir.
Peter Brook | Stony Brook University | Saw Mill River Parkway | Michael Brook | Stony Brook | Long Island Motor Parkway | Corner Brook | Blue Ridge Parkway | Garden State Parkway | Brook Benton | Stony Brook, New York | Rea Brook | Porter Brook | Parkway Drive | Harpers Brook | Didcot Parkway railway station | Taconic State Parkway | Robert Brook Aspland | Northern State Parkway | Merritt Parkway | Kelly Brook | Hutchinson River Parkway | Holy Brook | Foudry Brook | Brook Taylor | Brook Farm | Black Brook | Willow Brook | Wantagh State Parkway | Utopia Parkway |
The road is a major thoroughfare in the county and provides access to the New York State Thruway, Saw Mill River Parkway, Sprain Brook Parkway and Bronx River Parkway, four of the major roads in the county.