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U.S. Route 66, the historic US highway between Chicago, Illinois and Santa Monica, California, passed through one brief segment in the southeastern corner of Kansas.
Business US Highway 131 (BUS US 131) is a business route running through downtown Constantine.
There are six business routes of US Highway 131 in the state of Michigan.
U.S. Route 140, a former US highway designation—the northern portion of which had been the Gettysburg and Petersburg Turnpike.
U.S. Route 217 (US 217) was an original US highway, established in 1926, and was completely overlapped with NC 22.