It has been argued that the genetic and structural evidence supporting the model simply shows BiP dissociation to be merely correlated with Ire1 activation, rather than specifically causing it.
protein | Protein subunit | Protein-protein interaction | Hfq protein | protein domain | Protein-protein_interaction | Protein Data Bank | RNA-binding protein | Promyelocytic leukemia protein | Interactive voice response | G protein | Wiskott–Aldrich syndrome protein | Protein G | protein dimer | Protein A | C-reactive protein | Bone morphogenetic protein 2 | AMP-activated protein kinase | American Medical Response | Transmembrane protein | The Relaxation Response | The Burning Tigris: The Armenian Genocide and America's Response | Tau protein | Sterol regulatory element-binding protein | SR protein | Rab escort protein | Protein structure | protein structure | Protein phosphatase 2 | protein kinase |