In a procedure first attempted at Moorfields Eye Hospital in London, researchers at the John Radcliffe Hospital in Oxford have used gene therapy to attempt to curtail the condition which is caused by a faulty gene labelled REP1 and causes the light sensitive cells in the eye to gradually die.
Instead, Rab proteins are bound by the Rab escort protein (REP) over a more conserved region of the Rab protein and then presented to the Rab geranylgeranyltransferase.
protein | Protein subunit | Protein-protein interaction | Hfq protein | protein domain | Protein-protein_interaction | Protein Data Bank | Ford Escort | RNA-binding protein | Rab C. Nesbitt | Promyelocytic leukemia protein | G protein | Wiskott–Aldrich syndrome protein | Rab Butler | Protein G | protein dimer | Protein A | Ford Escort (Europe) | C-reactive protein | Bone morphogenetic protein 2 | AMP-activated protein kinase | Transmembrane protein | Tau protein | Sterol regulatory element-binding protein | SR protein | Rab geranylgeranyltransferase | Rab escort protein | Rab concentration camp | Protein structure | protein structure |