RNA-binding protein | Binding of Isaac | binding | The Binding of Isaac | Sterol regulatory element-binding protein | Methyl-CpG-binding domain | Karl Binding | DNA-binding domain | Comb binding | Coil binding | C4b-binding protein | Binding (molecular) | The Binding of Isaac (video game) | Sex hormone-binding globulin | penicillin binding proteins (PBPs) | Penicillin binding proteins | List of binding knots | Lee Binding | Insulin-like growth factor-binding protein | E3 binding protein | Dos-à-dos binding | Disc-binding | CREB-binding protein | Chemical affinity | chemical affinity | Binding selectivity | binding domain | ATP-binding cassette transporter |
The PDBbind database is a comprehensive collection of experimentally measured binding affinity data (Kd, Ki, and IC50) for the protein-ligand complexes deposited in the Protein Data Bank (PDB).
These compounds are primarily used in scientific research, as their high binding affinity for monoamine transporters, and the wide range of radiolabelled phenyltropane compounds available with different binding specificities makes them very useful for mapping the distribution of the various monoamine transporters in the brain.
Allosteric enzymes are enzymes that change their conformational ensemble upon binding of an effector, which results in an apparent change in binding affinity at a different ligand binding site.
In 1903, Christian Bohr described the phenomenon, now called the Bohr effect, whereby hydrogen ions and carbon dioxide heterotopically decrease hemoglobin's oxygen-binding affinity.
Aldolase has also been implicated in many "moonlighting" or non-catalytic functions, based upon its binding affinity for multiple other proteins including F-actin, α-tubulin, light chain dynein, WASP, Band 3 anion exchanger, phospholipase D (PLD2), glucose transporter GLUT4, inositol trisphosphate, V-ATPase and ARNO (a guanine nucleotide exchange factor of ARF6).
A correlation has been drawn between the binding affinity of seletracetam (and its analogues) to SV2A and the degree of seizure prevention in animal models.
Telmisartan is an angiotensin II receptor blocker that shows high affinity for the angiotensin II receptor type 1 (AT1), with a binding affinity 3000 times greater for AT1 than