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4 unusual facts about mesenchymal stem cell


Anterior cruciate ligament reconstruction

Recently, autologous stem cell transplantation using mesenchymal stem cells (MSCs) has been used to improve recovery time from ACL surgery, especially for athletes.

Intramembranous ossification

Mesenchymal stem cells within mesenchyme or the medullary cavity of a bone fracture initiate the process of intramembranous ossification.

Primitive streak

To form the streak, reptiles, birds and mammals arrange mesenchymal cells along the prospective midline, establishing the second embryonic axis, as well as the place where cells will ingress and migrate during the process of gastrulation and germ layer formation.

Tendinitis

Mesenchymal stem cells, derived from a horse's bone marrow or fat, are currently being used for tendon repair in horses.


Mir-598 microRNA precursor family

miR-598 has been shown to directly target and inhibit the Sir2 homolog, silent information regulator one (SRT1) enzyme, in the senescence of human adipose-tissue-derived mesenchymal stem cells.


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