X-Nico

3 unusual facts about signal transduction


Insulin signal transduction pathway and regulation of blood glucose

Insulin secretion mechanism is a common example of Signal transduction pathway mechanism.

Signal transduction is a mechanism in which the cell responds to a signal from the environment by activating several proteins and enzymes that will give a response to the signal.

Transduction

Signal transduction, any process by which a biological cell converts one kind of signal or stimulus into another


12-O-Tetradecanoylphorbol-13-acetate

12-O-Tetradecanoylphorbol-13-acetate (TPA), also commonly known as tetradecanoylphorbol acetate, tetradecanoyl phorbol acetate, and phorbol 12-myristate 13-acetate (PMA), is a diester of phorbol and a potent tumor promoter often employed in biomedical research to activate the signal transduction enzyme protein kinase C (PKC).

PLEKHM3

PLEKHM3 is thought to interact with a protein called GDAP1, which is responsible for differentiation in neuronal cell types and plays a role in the signal transduction pathway.

Transforming growth factor beta superfamily

These proteins interact with a conserved family of cell surface serine/threonine-specific protein kinase receptors, and generate intracellular signals using a conserved family of proteins called SMADs.


see also

CD134

TRAF3 may play a critical role in OX40-mediated signal transduction.

Dario Alessi

Dario Alessi FRSE FRS (born in France, 1967) is a biochemist, Director of the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) and Professor of Signal Transduction, at University of Dundee.

Interleukin-1 receptor

The IL-1 receptor accessory protein (IL1RAP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction.

Juxtacrine signalling

The term "juxtacrine" was originally introduced by Anklesaria et al. (1990) to describe a possible way of signal transduction between TGF alpha and EGFR.

TNFRSF21

Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors.