Enteropathy associated T-cell lymphoma (EATL) is environmentally induced as a result of the consumption of Triticeae glutens (e.g. wheat gluten).
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To make this diagnosis under its present system of classification, the WHO the presence of "hallmark" cells and immunopositivity for CD30.
IPEX (immunodysregulation polyendocrinopathy enteropathy X-linked syndrome) is a rare disease linked to the dysfunction of the transcription factor FOXP3, widely considered to be the master regulator of the regulatory T cell lineage.
This may be a clinical sign of hypoalbuminaemia (low albumin), which can be seen in nephrotic syndrome (a form of kidney failure), liver failure, protein malabsorption and protein-losing enteropathies.
Causes of protein losing enteropathy include celiac disease, Crohn's disease, short bowel syndrome (where the absorptive area for proteins is decreased), intestinal lymphangiectasia, amyloidosis, enteropathy caused by NSAIDs, Ménétrier's disease, dyskeratosis congenita, IPEX and giardiasis.
In 2005, Sullo was forced to temporarily quit football because of a B-cell lymphoma, but fully recovered and returned playing within eight months' time.
The impetus for Torrey's work in patient empowerment and patient advocacy stemmed from her diagnosis in 2004 of Subcutaneous T-cell lymphoma when she was told she had only months to live and was encouraged to undergo chemotherapy to treat it.