X-Nico

3 unusual facts about Protein kinase


Protein kinase

Kinases are turned on or off by phosphorylation (sometimes by the kinase itself - cis-phosphorylation/autophosphorylation), by binding of activator proteins or inhibitor proteins, or small molecules, or by controlling their location in the cell relative to their substrates.

Protein kinase, AMP-activated, alpha 1

Protein kinase, AMP-activated, alpha 1 has been shown to interact with TSC2.

It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK).


IRAK4

IRAK-4 (interleukin-1 receptor-associated kinase 4), in the IRAK family, is a protein kinase involved in signaling innate immune responses from Toll-like receptors.

Multipolar spindles

A possible causes of multipolar spindle formation involve regulation of protein kinase family known as Aurora kinase.


see also

MTORC2

It is composed of mTOR, rapamycin-insensitive companion of mTOR (RICTOR), GβL, and mammalian stress-activated protein kinase interacting protein 1 (mSIN1).

Pom1

Pom1 is a polarity protein kinase in fission yeast, Schizosaccharomyces pombe (S. pombe), that localizes to cell ends and regulates cell division.

Tyrosine-protein kinase BLK

The tyrosine-protein kinase BLK has been shown to interact with UBE3A.