X-Nico

2 unusual facts about membrane protein


Solid-state nuclear magnetic resonance

Membrane proteins and amyloid fibrils, the latter related to Alzheimer's disease and Parkinson's disease, are two examples of application where solid-state NMR spectroscopy complements solution-state NMR spectroscopy and beam diffraction methods (e.g. X-ray crystallography, electron microscopy).

TNFSF12-TNFSF13

The hybrid protein is membrane anchored and presents the receptor-binding domain of the family member 13 at the cell surface.


Crystallographic image processing

Aaron Klug suggested in 1979 that a technique that was originally developed for structure determination of membrane protein structures can also be used for structure determination of inorganic crystals.


see also

Behavioral neuroscience

Synapto-pHluorin is a technique that relies on a fusion protein that combines a synaptic vesicle membrane protein and a pH sensitive fluorescent protein.

CLEC4C

CLEC4C is a membrane protein of plasmacytoid dendritic cells, which is used as a marker for this kind of cells and denoted as CD303 in the nomenclature of the Cluster of differentiation.

KCNE1L

This gene encodes a membrane protein that has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily.

Vibrio regulatory RNA of OmpA

VrrA (Vibrio regulatory RNA of OmpA) is a non-coding RNA that is conserved across all Vibrio species of bacteria and acts as a repressor for the synthesis of the outer membrane protein OmpA.