GSK716155 (Albugon) is a recombinant human glucagon-like peptide (GLP)-1-Albumin protein created using Human Genome Sciences' proprietary albumin fusion technology, which involves fusing the gene that expresses human albumin to the gene that expresses a therapeutically active protein (GLP-1)1.
Recombinant HCG (rHCG), recombinant luteinizing hormone (rLH) and urine-derived hCG (uHCG) are equally effective in achieving final follicular maturation in IVF with regards to pregnancy rates and risk of ovarian hyperstimulation syndrome.
recombinant | Recombinant DNA | recombinant DNA | Recombinant |
The recombinant enzyme from the plant Arabidopsis thaliana produces (+)-alpha-barbatene, (+)-thujopsene and (+)-beta-chamigrene.
--> Adalimumab (which is a humanized recombinant antibody to TNF) showed effectiveness in patients with moderate-to-severe Crohn's disease, but less than that of infliximab.
WC-rBS (marketed as "Dukoral") is a monovalent inactivated vaccine containing killed whole cells of V. cholerae O1 plus additional recombinant cholera toxin B subunit.
Tobinick has been issued patents for methods of perispinal administration, of certain recombinant DNA-derived (biologic) therapeutics including the TNF receptor fusion protein etanercept, for the treatment of certain neurologic disorders with widespread unmet medical need, including Alzheimer's disease; pain due to cancer metastasis to bone; severe, intractable, intervertebral disc-related pain and radiculopathy (including sciatica); and myasthenia gravis.
Enzo Paoletti is an Italian scientist who devised a strategy to produce recombinant DNA vaccines.
Spodoptera frugiperda cells (Sf9 and Sf21 cell lines) are commonly used in biomedical research for the purpose of recombinant protein expression using insect-specific viruses called baculoviruses.
Merial produces a recombinant vaccine consisting of canarypox virus carrying FeLV gag and env genes (sold as PUREVAX FeLV in the USA and Eurifel FeLV in Europe).
BioSteel is a trademark name for a high-strength based fiber material made of the recombinant spider silk-like protein extracted from the milk of transgenic goats, made by Nexia Biotechnologies.
It was withdrawn from the marketplace when Pablo DT Valenzuela, Research Director of Chiron Corporation succeeded in 1986 in making the antigen in yeast and invented the first recombinant vaccine.
Declining a position to work as a post-doctoral researcher with Stanley Cohen, the co-developer of recombinant DNA, Schoemaker entered the world of business.
-- Really "the best"? Or just good, on a disease that's easily treated? --> These patients were treated with the recombinant immunotoxin, BL22, which targets the CD22 cell surface receptor, which is highly expressed on these leukemic cells.
There are currently more than 100 insect cell lines available for recombinant protein production with lines derived from Bombyx mori, Mamestra brassicae, Spodoptera frugiperda, Trichoplusia ni, and Drosophila melanogaster being of particular interest.
In 2003 she was awarded the Royal Society's Gabor Medal "for her contributions to the isolation and manipulation of recombinant DNA molecules in a eukaryotic organism, adding a new dimension to molecular and cellular biology".
Under his leadership secretory and non-secretory expression systems for the production of recombinant proteins in E. coli, Saccharomyces cerevisiae, Baculovirus and mammalian cells in cell culture were developed and recombinant virus technology was established.
It is also based on the circumsporozoite protein, but additionally has the recombinant (Asn-Ala-Pro15Asn-Val-Asp-Pro)2-Leu-Arg(R32LR) protein covalently bound to a purified Pseudomonas aeruginosa toxin (A9).
In collaboration with Amgen, recombinant G-CSF (Neupogen) was developed and in 1987 the first clinical studies were begun at Memorial Sloan-Kettering in cancer patients and pediatric patients with a genetic form of neutropenia.
Nesiritide (Natrecor) is the recombinant form of the 32 amino acid human B-type natriuretic peptide, which is normally produced by the ventricular myocardium.
;Golden rice : a recombinant variety of rice that has been engineered to express the enzymes responsible for β-carotene biosynthesis.
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;Herbicide-resistant crops : commercial varieties of important agricultural crops (including soy, maize/corn, sorghum, canola, alfalfa and cotton) have been developed that incorporate a recombinant gene that results in resistance to the herbicide glyphosate (trade name Roundup), and simplifies weed control by glyphosate application.
It is the first Indian company to develop, manufacture and market recombinant human healthcare products in India.
Sprifermin as another name for human recombinant FGF18 and its manufacturers hope it will soon enter clinical trials for treatment of knee osteoarthritis.
The lipoprotein enhanced the ability of HDL, or “good” cholesterol to usher fat out of the arteries and into the liver for excretion leading to the purchase of Esperion Therapeutics, the tiny company that had produced recombinant Apo-A1 Milano, by Pfizer for $1.3 billion.
He was a pioneer in the technique of transferring recombinant genes to mice (transgenic mice) and in 1988 he and Philip Leder were granted a patent on a genetically engineered mammal.