X-Nico

4 unusual facts about recombinant DNA


Biological therapy for inflammatory bowel disease

--> Adalimumab (which is a humanized recombinant antibody to TNF) showed effectiveness in patients with moderate-to-severe Crohn's disease, but less than that of infliximab.

Recombinant DNA

;Golden rice : a recombinant variety of rice that has been engineered to express the enzymes responsible for β-carotene biosynthesis.

;Herbicide-resistant crops : commercial varieties of important agricultural crops (including soy, maize/corn, sorghum, canola, alfalfa and cotton) have been developed that incorporate a recombinant gene that results in resistance to the herbicide glyphosate (trade name Roundup), and simplifies weed control by glyphosate application.

Shantha Biotechnics

It is the first Indian company to develop, manufacture and market recombinant human healthcare products in India.


Cetus Corporation

By the late-1970s, however, three new revolutionary techniques had been developed: recombinant DNA, monoclonal antibodies, and gene expression, the foundations of the biotechnology industry.

Feline leukemia virus

Merial produces a recombinant vaccine consisting of canarypox virus carrying FeLV gag and env genes (sold as PUREVAX FeLV in the USA and Eurifel FeLV in Europe).

John Carbon

His research contributions include elucidation of the mechanism of genetic missense suppression in bacteria, the development of techniques to make genomic libraries using recombinant DNA, techniques for using yeast for DNA cloning, characterization of centromere DNA, and construction of the first artificial chromosomes.

Nesiritide

Nesiritide (Natrecor) is the recombinant form of the 32 amino acid human B-type natriuretic peptide, which is normally produced by the ventricular myocardium.


see also

Edward Tobinick

Tobinick has been issued patents for methods of perispinal administration, of certain recombinant DNA-derived (biologic) therapeutics including the TNF receptor fusion protein etanercept, for the treatment of certain neurologic disorders with widespread unmet medical need, including Alzheimer's disease; pain due to cancer metastasis to bone; severe, intractable, intervertebral disc-related pain and radiculopathy (including sciatica); and myasthenia gravis.

Enzo Paoletti

Enzo Paoletti is an Italian scientist who devised a strategy to produce recombinant DNA vaccines.

Hubert Schoemaker

Declining a position to work as a post-doctoral researcher with Stanley Cohen, the co-developer of recombinant DNA, Schoemaker entered the world of business.

Jean Beggs

In 2003 she was awarded the Royal Society's Gabor Medal "for her contributions to the isolation and manipulation of recombinant DNA molecules in a eukaryotic organism, adding a new dimension to molecular and cellular biology".