Sigma Chi | Sigma Xi | Sigma Alpha Epsilon | receptor | Delta Sigma Theta | LDL receptor | Receptor (biochemistry) | Continuous erythropoietin receptor activator | Phi Beta Sigma | GABA receptor | Epidermal growth factor receptor | Sigma Corporation | Sigma Alpha Mu | Sigma Phi Epsilon | Sigma | NMDA receptor | Kappa Sigma | Beta Gamma Sigma | Tau Beta Sigma | Six Sigma | Sigma Alpha Iota | Sensory receptor | receptor (biochemistry) | Phi Sigma Kappa | metabotropic glutamate receptor | 5-HT2A receptor | VLDL receptor | TGF beta receptor 2 | SK Sigma Olomouc | Sigma SD14 |
Its mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms.
sigma receptor agonist (Ki = 205 nM and 11,060 nM, respectively).