The head-twitch response (HTR) is a rapid side-to-side head movement that occurs in mice and rats after the serotonin 5-HT2A receptor is activated.
OSU-6162 (PNU-96391) is a compound which acts as a partial agonist at both 2A5-HT2A receptors.
receptor | LDL receptor | Receptor (biochemistry) | Continuous erythropoietin receptor activator | GABA receptor | Epidermal growth factor receptor | NMDA receptor | Sensory receptor | receptor (biochemistry) | metabotropic glutamate receptor | 5-HT2A receptor | VLDL receptor | TGF beta receptor 2 | receptor antagonist | epidermal growth factor receptor | 5-HT receptor | RAR-related orphan receptor alpha | Metabotropic glutamate receptor 5 | Metabotropic glutamate receptor 2 | G protein-coupled receptor | AMPA receptor | Adenosine A1 receptor | Toll-like receptor | TNF receptor associated periodic syndrome | taste receptor | Sigma-1 receptor | Receptor antagonist | Receptor activity-modifying protein | Pancreatic polypeptide receptor 1 | Nuclear receptor |
The mechanism that produces the hallucinogenic and entheogenic effects of 5-MeO-MiPT is thought to result primarily from MAO may be involved also.
Classical or serotonergic psychedelics (agonists for the LSD (also known as "acid"), psilocin (the active constituent of psilocybin mushrooms, commonly known as "magic mushrooms" or "shrooms"), mescaline (the active constituent of peyote), and DMT (the active constituent of ayahuasca and potentially an endogenous psychedelic compound).