X-Nico

unusual facts about G protein-coupled receptor


Menelas N. Pangalos

Dr. Pangalos has edited the book “Understanding G protein-coupled receptors in the CNS”, as well as a number of journal issues focused on drug discovery in the CNS.


Estrogen receptor

In addition, some ER may associate with cell membranes by attachment to caveolin-1 and form complexes with G proteins, striatin, receptor tyrosine kinases (e.g., EGFR and IGF-1), and non-receptor tyrosine kinases (e.g., Src).

Krzysztof Palczewski

His work with determining the crystal structure of rhodopsin has given new insight into the function of G protein receptors.

Pamoic acid

It was demonstrated that pamoic acid has agonist activity for the orphan G protein-coupled receptor GPR35 by which it activates ERK and beta-arrestin2, and causes antinociceptive activity.

Rac3

Rac3 (Ras-related C3 botulinum toxin substrate 3) is a small (~21 kDa) monomeric GTP-binding protein G protein and is an important component of intracellular signalling pathways.


see also

EBI2

G-protein coupled receptor 183 (GPR183), also known as Epstein-Barr virus-induced G-protein coupled receptor 2 (EBI2)

Retinal G protein coupled receptor

Retinal G protein coupled receptor has been shown to interact with KIAA1279.