X-Nico

unusual facts about Genome-wide association study


Jason H. Moore

He then applied MDR for improved understanding of the interplay of multiple genetic polymorphisms of complex traits in genome-wide association studies.


Abelson murine leukemia virus

As a retrovirus, it has a single-stranded, positive sense RNA genome which replicates via a DNA intermediate mediated by a reverse transcriptase.

Agrococcus

The first draft genome of the genus Agrococcus was completed by a group at the University of British Columbia that was isolated from modern microbialites found within Pavilion Lake, BC.

Aphthovirus

It consists of a single molecule of (+) sense RNA, with a 5' genome linked protein (VPg), which is associated to the genome via a phosphodiester bond linked to a tyrosine residue.

Biotechnology and genetic engineering in Bangladesh

In 2012, the same group of scientists decoded the genome of Macrophomina phaseolina, a Botryosphaeriaceae fungus, which is responsible for causing seedling blight, root rot, and charcoal rot of more than 500 crop and non-crop species throughout the world.

Blastocystis

The genome encodes several subunits of NADH dehydrogenase (complex I) but lacks all trace of genes for cytochrome and ATPase subunits (Complexes III-V).

Brazilian large-eyed stingray

In 2006, Leticia de Almeida Leao Vaz and colleagues published a phylogenetic analysis, based on genomic DNA, of the Brazilian large-eyed stingray and three other common stingrays found off Brazil: the southern stingray (D. americana), the longnose stingray (D. guttata), and the roughtail stingray (D. centroura).

Conjoined gene

However, only a very limited number of these CGs are found in the public human genome resources such as the Entrez Gene database, the UCSC Genome Browser and the Vertebrate Genome Annotation (Vega) database.

Critical Art Ensemble

This participatory performance was titled Cult of the New Eve (or CoNE when abbreviated) and included a "communion" using a random library of the entire genome of the first female donor to the Human Genome Project taken from a blood sample.

Exome sequencing

Individuals have had access to whole genome sequencing services for some time through companies like Illumina and Knome, but at a cost of several thousand dollars and often the services were geared toward researchers.

FAIRE-Seq

FAIRE-seq data are mapped to the human genome assembly and displayed as part of the ENCODE project at the UCSC Genome Browser.

GenoMik

#The competence network Würzburg, "genome research on pathogenic bacteria", coordinated by Professor Werner Goebel.

Gerald M. Rubin

Gerald Mayer Rubin (born 1950) is an American biologist, notable for pioneering the use of transposable P elements in genetics, and for leading the public project to sequence the Drosophila melanogaster genome.

Hinxton

Since 1992, the hall has been occupied by the Wellcome Trust Genome Campus and has housed their pioneering genome-sequencing project.

Hugo Van Heuverswyn

He obtained a chemistry degree at University of Ghent in 1971, and he obtained a Ph.D. at the Department of Molecular Biology, under Prof. Walter Fiers, where together with his colleagues, he determined for the first time the structure and regulatory mechanisms of a complete viral DNA genome: the virus SV40.

Human Microbiome Project

The microbial genome data were extracted by identifying the bacterial specific ribosomal RNA, 16S rRNA.

Hybrid genome assembly

This approach was used to sequence the genome of a strain of Vibrio cholerae that was responsible for a cholera outbreak in Haiti.

International Committee on Taxonomy of Viruses

The database classifies viruses based primarily on their chemical characteristics, genomic type, nucleic acid replication, diseases, vectors, and geographical distribution, among other characteristics.

John Abelson

His work has made possible an understanding of how genomic DNA can be converted to both messenger RNA and transfer RNA, particularly when there are introns present in the genome.

Jumping plant louse

Thus far, 10 microbial organisms have been identified within these psyllids, among them the primary endosymbiont, whose genome has been sequenced and posted at the NCBI database, as well as a Wolbachia species.

Lagovirus

The 5' end of the genome has a usually genome-linked protein (VPg), or methylated nucleotide cap (in the case of Hepatitis E virus).

Metaviridae

An example of this is the gypsy, a retroelement found in the Drosophila melanogaster genome.

Michael D. Mehta

He has received numerous awards such as Chief Scientist Distinguished Lecturer for Outstanding Contributions in the Field of Science, Technology, Advancement of Science, Health Canada (2007), The Saskatchewan Centennial Medal (2006), and Agriculture Genomics Award, Genome Canada (2003).

Midichloria

The genome of Midichloria mitochondrii was recently sequenced by an international scientific consortium formed by researchers belonging to the University of Milan, the University of Sydney, the University of Valencia, the University of Pavia, and the University of Milan Bicocca.

MITES

Genomics - Students research DNA and genetic diseases at the Broad Institute, where one third of the human genome was sequenced.

Mnemiopsis

The genome of Mnemiopsis leidyi appears to lack recognizable microRNAs, as well as the nuclear proteins Drosha and Pasha, which are critical to canonical microRNA biogenesis.

Murine leukemia virus

The genome includes a conserved RNA structural element called a core encapsidation signal that directs packaging of RNA into the virion; the tertiary structure of this element has been solved using nuclear magnetic resonance spectroscopy.

National Human Genome Research Institute

November 17, 2009 - NIH Appoints Eric D. Green, M.D., Ph.D. to be Director of The National Human Genome Research Institute.

NeuN

The mammalian genome contains three genes homologous to C. elegans Fox-1, called Fox-1, Fox-2 and Fox-3.

Obestatin

Research carried out at the Stanford University School of Medicine in 2005 identified obestatin as a new hormone with a bioinformatics approach by computer search of the sequenced genomes of several organisms.

Ocimum tenuiflorum

In a large-scale phylogeographical study of this species conducted using Chloroplast genome sequences, a group of researchers from Central University of Punjab, Bathinda have found that this plant had been originated in North-Central India.

Oscarella carmela

Analysis of the genome suggests that the last common ancestor of sponges and eumetazoan animals (a clade that contains all the higher animals except the sponges and placozoans) was more complex both genetically and morphologically than had previously been thought.

Paenibacillus dendritiformis

The genome was sequenced by a hybrid approach using 454 Life Sciences and Illumina, achieving a total of 340X coverage, with 99.8% sequence identity between the two methods.

Partitiviridae

The genome segments are packaged in the same virus particle, the larger segment codes for the RNA-dependent RNA polymerase and the smaller codes for the coat protein.

Patent Lens

For agriculture and the environment, landscapes exist to describe the Agrobacterium-mediated transformation of plants, promoters used to regulate gene expression, antibiotic resistance genes and their uses in plant genetic transformation, resistance to Phosphinothricin, positive selection, bioindicators/ambiosensors, and the rice genome.

Pectinesterase

Recently, the systematic sequencing of the Arabidopsis thaliana genome has led to the identification of 66 open reading frames that are annotated as pectinesterases, most of which are encoded as large pre-proproteins.

Phenotype mixing

Phenotype mixing is a form of interaction between two virus particles, each of which holds its own unique genetic material.

PhiKMV-like viruses

Although phiKMV phage resembles the well-studied podovirus T7 in overall genome architecture, it was the first known T7-like phage which encoded a single-subunit RNA polymerase gene downstream its DNA metabolism genes instead of in the early genomic region.

Polony sequencing

Also, it is a very flexible technique that enables variable application including BAC (bacterial artificial chromosome) and bacterial genome resequencing, as well as SAGE (serial analysis of gene expression) tag and barcode sequencing.

Polynucleobacter

Analyses of the genome sequences resulted in the discovery of a conserved RNA motif.

Pyrococcus furiosus

The sequencing of the complete genome of Pyrococcus furiosus was completed in 2001 by scientists at the University of Maryland Biotechnology Institute.

Renato Dulbecco

As demonstrated by Temin and Baltimore, who shared the Nobel Prize with Dulbecco, the transfer of viral genes to the cell is mediated by an enzyme called reverse transcriptase (or, more precisely, RNA-dependent DNA polymerase), which replicates the viral genome (in this case made of RNA) into DNA, which is later incorporated in the host genome.

RNF213

A genome-wide association study identified RNF213 as the first gene associated to Moyamoya disease.

Saccharomyces Genome Database

The Saccharomyces Genome Database is a scientific database of the molecular biology and genetics of the yeast Saccharomyces cerevisiae, which is commonly known as baker's or budding yeast.

Sciaridae

The Sciaridae practice paternal genome elimination, whereby the male passes on only the genetic material of his mother to his offspring.

Small nucleolar RNA R41

snoR41 was identified by computational screening the rice Oryza sativa genome and is predicted to act as a methylation guide for 18S and 25S ribosomal RNA (rRNA).

Synthetic genomics

The J. Craig Venter Institute has assembled a quasi-synthetic Mycoplasma genitalium yeast genome by recombination of 25 overlapping fragments in a single step.

Technical Presentation

In his book, Presentations for Dummies, Malcolm Kushner’s chapter on “Technical and Financial Presentations” includes comments by Dr. David Haussler, the mastermind of the human genome project and an expert on technical presentations.

Uniparental inheritance

Carl Erich Correns and Erwin Baur, in separately conducted researches on Pelargonium and Mirabilis plants, observed a green-white variation (later found as the result of mutations in the chloroplast genome) that did not follow the Mendelian laws of inheritance.


see also