The recruited eosinophils will degranulate releasing a number of cytotoxic molecules (including Major Basic Protein and eosinophil peroxidase) as well as produce a number of cytokines such as IL-5.
In EG cytokines IL-3, IL-5 and granulocyte macrophage colony stimulating factor (GM-CSF) may be behind the recruitement and activation.
The granulocyte macrophage colony-stimulating factor receptor is a heterodimer composed of at least two different subunits; an α chain, and a β chain which is also present in the receptors for IL-3 and IL-5.
Interleukin 3 | Interleukin 6 | Interleukin 5 | Interleukin 18 | Interleukin 17 | Interleukin 4 | Interleukin 15 | Interleukin 8 | Interleukin 32 | Interleukin 24 | Interleukin 2 | Interleukin 12 | interleukin 6 (IL-6) | Interleukin-3 receptor | Interleukin 22 | Interleukin 13 | Interleukin 12 receptor, beta 2 subunit | Interleukin 10 |