It was released in July 1994 as the second single from his debut album, Regulate...G Funk Era.
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It is designed to specifically inhibit and down-regulate at a cell level the production of human ICAM-1 protein.
These shutters,operated by Traction motors help to regulate the flow of saline water entering into the neighboring paddy fields of Thuravoor, Pattanakad, Ezhupunna, Kuthiathode panchayats connected to the back waters.
The AN2 region of the short arm of chromosome 11 (11p13) includes the PAX6 gene (named for its PAired boX status), whose gene product helps regulate a cascade of other genetic processes involved in the development of the eye (as well as other nonocular structures).
The Executive Board shall process the applications of new members and regulate the activities of ANN.
Border control, the measures used by a country to monitor or regulate its borders
The Bretton Woods Conference, formally known as the United Nations Monetary and Financial Conference, was the gathering of 730 delegates from all 44 Allied nations at the Mount Washington Hotel, situated in Bretton Woods, New Hampshire, United States, to regulate the international monetary and financial order after the conclusion of World War II.
In addition, other financial regulators, including the Federal Reserve System, the Office of the Comptroller of the Currency (OCC), and the Federal Deposit Insurance Corporation (FDIC) among others, are also developing margin requirements that would apply to the entities they regulate.
LRP5 (low-density lipoprotein receptor-related protein 5) acts as a co-receptor for the Wnt-family of glycoproteins which regulate bone mass.
Voltage source, electrical power source that regulate voltage to a constant level
Legislation to regulate cruise ship discharges of sewage, graywater, and bilge water nationally was introduced in the 109th Congress, but there was no further congressional action.
Finally, DHEA is thought to regulate a handful of other proteins via indirect, genomic mechanisms, including the enzymes P4502C11 and 11β-HSD1—the latter of which is essential for the biosynthesis of the glucocorticoids such as cortisol and has been suggested to be involved in the antiglucocorticoid effects of DHEA—and the carrier IGFBP1.
Therefore, some economists, including John Geanakoplos, strongly argue that the Federal Reserve should monitor and regulate the system-wide leverage level in the economy, limiting leverage in good times and encouraging higher levels of leverage in bad times, by extending lending facilities.
During the Civil War, he served as colonel of a militia regiment in 1864 and was an appraiser of the Confederate States Government to regulate the value of the Confederate dollar.
The National Association of Realtors put forth the Internet Listing Display (ILD) which is a set of rules that regulate how homes and properties can be displayed on Web sites.
The definied European Union wine growing zones are used to regulate these practices, but some leeway is given for authorising deviations in vintages of exceptional climatic conditions.
Its purpose is to regulate the services provided by opticians and optometrists (ophthalmic opticians).
Gun law in the United States, federal laws that regulate firearms and ammunition at a national level
He immediately tried to regulate Frisian shipping and ignored the privileges granted to the town of Staveren.
Non-human SIVs contain a nef gene that down-regulates CD3, CD4, and MHC class I expression; most non-human SIVs, therefore, do not induce immunodeficiency; the HIV-1 nef gene, however, has lost its ability to down-regulate CD3, which results in the immune activation and apoptosis that is characteristic of chronic HIV infection.
"I am gross and perverted. I'm obsessed 'n deranged. I have existed for years, but very little had changed. I am the tool of the Government and industry too, for I am destined to rule and regulate you. I may be vile and pernicious, but you can't look away. I make you think I'm delicious, with the stuff that I say. I am the best you can get. Have you guessed me yet?"
Readers can rate reviewers in a similar way that online retailers such as Amazon.com self-regulate their evaluations.
In 2008 Ernst Hirsch Ballin, then Minister of Justice, proposed a plan to regulate the blocking of websites known to contain child pornography.
Resnick played a central role in passing the Animal Welfare Act of 1966, which empowered the United States Department of Agriculture (USDA) to protect and regulate the use of animals in research facilities.
The controversial nature of the coverage led to calls for a body to regulate and oversee standards in the Irish press similar to the Press Complaints Commission in the UK.
In 1944, before the conclusion of World War II, delegates from the 44 allied nations gathered in Bretton Woods, New Hampshire, United States, to reestablish and regulate the international financial systems.
The Maharashtra State Board of Secondary Education, Pune came into existence on January 1, 1966 to regulate certain matters pertaining to secondary education in the state of Maharashtra, India.
Separate bodies regulate the legal profession in the states of Sabah and Sarawak.
They knew that the U.S. Environmental Protection Agency (EPA) was threatening to regulate workplace smoking as a carcinogenic pollutant in the ambient air—and therefore that their old standby claims that the 'smoker made the choice to smoke or not'... that smoking was a personal choice... would no longer excuse the damage to health.
In April 2007 the Board drafted guidelines aimed at stopping doctors exaggerating their expertise and also banning "before" and "after" photos in advertising to regulate the cosmetic surgery industry.
miR-134 is a brain-specific microRNA; in rats it is localised specifically in hippocampal neurons and may indirectly regulate synaptic development through antisense pairing with LIMK1 mRNA.
The draft Mpumalanga Witchcraft Suppression Bill of 2007 expanded on the Witchcraft Suppression Act of 1957, defining witchcraft as harmful magic and attempting to regulate the conduct of traditional healers in Mpumalanga.
They negatively regulate the expression of several genes encoding outer membrane proteins, including cirA, CsgD, fecA, fepA and ompT by binding in the vicinity of the Shine-Dalgarno sequence, suggesting the control of these targets is dependent on Hfq protein and RNase E.
Osteocyte specific proteins such as sclerostin have been shown to function in mineral metabolism, as well as other molecules such as PHEX, DMP-1, MEPE, and FGF-23, which are highly expressed by osteocytes and regulate phosphate and biomineralization.
For agriculture and the environment, landscapes exist to describe the Agrobacterium-mediated transformation of plants, promoters used to regulate gene expression, antibiotic resistance genes and their uses in plant genetic transformation, resistance to Phosphinothricin, positive selection, bioindicators/ambiosensors, and the rice genome.
However, AMPK is an enzyme found in many more types of cells than chemoreceptors because it helps regulate metabolism.
In 1821 Rajmund Rembieliński - the president of the Commission of the Province of Mazovia - took some action in order to regulate the building development in the industrial settlement.
The Plant Quarantine Act, originally enacted in 1912 (7 U.S.C. 151 et seq.), gave the Animal and Plant Health Inspection Service (APHIS) authority to regulate the importation and interstate movement of nursery stock and other plants that may carry pests and diseases that are harmful to agriculture.
In 1867, the Attorney-General for Ireland, Hedges Eyre Chatterton, issued guidelines to regulate which cases ought to be tried at tried at assizes rather than quarter sessions: treason, murder, treason felony, rape, perjury, assault with intent to murder, party processions, election riots, and all offences of a political or insurrectionary character.
In 1868, Chambers's Encyclopaedia noted that the Queen's Regulations for the Navy "in a great degree regulate matters of finance; whereas, in the army, financial matters are left to the War Office regulations".
EPA is responsible for issuing permits that regulate the disposal of materials at sea (except for dredged material disposal, for which the U.S. Army Corps of Engineers is responsible).
E. Tory Higgins states, “When people self-regulate they decide what they want that they don’t currently have. They then figure out what they need to do to get what they want, and then they do it”.
Researchers at the University of Florida's College of Medicine have developed a way to air condition shoulder pads that is designed to regulate players' body temperatures during games and practices.
The SMCR7L gene codes for a protein that has been called MiD51/MIEF1 and shown to regulate mitochondrial fission by interacting with the proteins Drp1 and FIS1.
The book explores the US Supreme Court case Dred Scott v. Sandford, in which the court ruled that the federal government could not regulate slavery in the territories.
The first Standard State Zoning Enabling Act, (or "SZEA") was written by a New York City commission headed by Edward Bassett and signed by Mayor John Purroy Mitchel in 1916 to regulate buildings and land usage in New York City.
According to its website, the mandate of the commission is "to supervise and regulate the insurance industry in Uganda." Commission offices are located in Kampala; the position of Commissioner of Insurance is currently vacant.
For instance, in the European Union, each member state must regulate unfair business practices in accordance with the Unfair Commercial Practices Directive, subject to transitional periods.
When amateur wrestling, especially freestyle wrestling, gained prominence as an amateur sport after the Civil War, the Amateur Athletic Union first began to regulate it, sponsoring national tournaments and local athletic clubs in amateur wrestling.