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Studies in 2006 showed evidence of a linkage between idiopathic scoliosis and three microsatellite polymorphisms in the MATN1 gene (encoding for Matrilin 1, cartilage matrix protein), respectively consisting of 103, 101 and 99 base pairs, .
For example, the internal palindrome sequence can be 4 to 8 base pairs in length and vary in the order of bases, however the pattern, 5'-Pu Pu CG Pu Py CG Py Py-3', was found to be the most active when compared to several other sequences.
Human Genome Project, is an international scientific research project with a primary goal of determining the sequence of chemical base pairs which make up DNA
The genome, consisting of 16,036 base pairs shows a large section of over 11,000 base pairs which are noncoding.