X-Nico

unusual facts about nucleoside-diphosphate kinase



Crofelemer

Crofelemer (USAN, trade name Fulyzaq) is a drug under development for the treatment of diarrhea associated with anti-HIV drugs such as nucleoside analog reverse transcriptase inhibitors and protease inhibitors.

Deoxyadenosine

It is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2' position of its ribose sugar moiety.

Enocitabine

Enocitabine (INN, marketed under the brand name Sunrabin) is a nucleoside analog used as chemotherapy.

Pseudouridine

Pseudouridine (abbreviated by the Greek letter psi- Ψ) is the C-glycoside isomer of the nucleoside uridine, and it is the most prevalent of the over one hundred different modified nucleosides found in RNA.

Queuosine

Florian Klepper, Eva-Maria Jahn, Volker Hickmann, Thomas Carell: „Synthesis of the Transfer-RNA Nucleoside Queuosine by Using a Chiral Allyl Azide Intermediate“, Angewandte Chemie International Edition, 2007, 46 (13), pp.

RAR-related orphan receptor alpha

The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.

RAR-related orphan receptor beta

The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside-diphosphate kinase involved in organogenesis and differentiation.

Rega Institute for Medical Research

The Nucleoside analogs, d4T, 3'-fluoro-3'-deoxythymidine (FLT) and 3'-fluorodideoxyguanosine (FLG), and the NNRTI's 1-(2-hydroxy-ethoxy) methyl-6-phenylthiothymine (HEPT), tetrahydro-imidazo4,5,1-jk1,4-benzodiazepine-2(1H)-one and -thione (TIBO) and alpha-anilinophenylacetamide (alpha-APA) were first described at the Rega Institute.


see also