Karl Kaspar von Siebold (November 4, 1736 – April 3, 1807) was a German surgeon and obstetrician who was a native of Nideggen.
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At length he left Southern Germany and took his residence in Berlin from 1794 to 1798, where he got into contact with Barthel von Siebold, a son of a Würzburg surgeon Karl Kaspar von Siebold.