X-Nico

2 unusual facts about messenger RNA


Messenger RNA

Upon export from the nucleus the mRNA associates with ZBP1 and the 40S subunit.

Transfer-messenger RNA

The complete E. coli tmRNA secondary structure was elucidated by comparative sequence analysis and structural probing.


Benoit Coulombe

Benoit Coulombe is a Canadian scientist whose research focuses on the mechanisms by which regulated protein–protein, protein–DNA and protein–RNA interactions control the activity of RNA polymerase II, the molecular machine that synthesizes all messenger RNA (mRNA) and some small-nuclear RNA (snRNA) in eukaryotes.

Minor spliceosome

The minor spliceosome is a ribonucleoprotein complex that catalyses the removal (splicing) of an atypical class of spliceosomal introns (U12-type) from eukaryotic messenger RNAs in plant, insects, vertebrates and some fungi (Rhizopus oryzae).

S-Adenosyl methionine

Methyltransferases are also responsible for the addition of methyl groups to the 2' hydroxyls of the first and second nucleotides next to the 5' cap in messenger RNA.

WHEP-TRS protein domain

EPRS is a component of the interferon-gamma-activated inhibitor of translation (GAIT) complex, which interacts with stem-loop elements (GAIT elements) in mRNAs encoding proinflammatory proteins, for example, vascular endothelial growth factor-A (VEGFA).


see also

John Abelson

His work has made possible an understanding of how genomic DNA can be converted to both messenger RNA and transfer RNA, particularly when there are introns present in the genome.

Mir-205

Micro-RNA-205 induced the expression of tumor suppressor genes IL-24 and IL-32 at both the messenger RNA and protein levels.