X-Nico

2 unusual facts about transfer RNA


Luidia

This has been shown to take place both in the field and in laboratory cultures and has been studied by molecular analysis of sequences of mitochondrial tRNA to identify the taxa involved.

Pseudouridine

It is commonly found in tRNA, associated with thymidine and cytosine in the TΨC arm and is one of the invariant regions of tRNA.The function of it is not very clear, but it is expected to play a role in association with aminoacyl transferases during their interaction with tRNA, and hence in the initiation of translation.


Polyadenylation

They have separately evolved in both bacteria and eukaryotes from CCA-adding enzyme, which is the enzyme that completes the 3' ends of tRNAs.


see also

DNA methylation

Finally, DNMT2 (TRDMT1) has been identified as a DNA methyltransferase homolog, containing all 10 sequence motifs common to all DNA methyltransferases; however, DNMT2 (TRDMT1) does not methylate DNA but instead methylates cytosine-38 in the anticodon loop of aspartic acid transfer RNA.

John Abelson

His work has made possible an understanding of how genomic DNA can be converted to both messenger RNA and transfer RNA, particularly when there are introns present in the genome.

Queuosine

Florian Klepper, Eva-Maria Jahn, Volker Hickmann, Thomas Carell: „Synthesis of the Transfer-RNA Nucleoside Queuosine by Using a Chiral Allyl Azide Intermediate“, Angewandte Chemie International Edition, 2007, 46 (13), pp.